These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Protein-nitrogen metabolism in the liver of rats intraperitoneally administered carminomycin].
    Author: Vetoshkina TV, Gol'dberg ED, Sal'nik BIu, Bakhareva GI.
    Journal: Antibiotiki; 1979 Feb; 24(2):127-33. PubMed ID: 434802.
    Abstract:
    It was found in the experiments with rats that in response to carminomycin administration in a single LD50 and the therapeutic doses during the treatment course the intracellular fond of the amino acids in the liver tissue increased, the autolytic processes activated, the activity of the transamination enzymes, histidine and ammonia lyases increased. The level of the residual nitrogen increased mainly at the expense of increased ammonia production and urea levels. These changes were more pronounced when the antibiotic was administered in LD50. Independent of the administration multiplicity and the antibiotic dosage they were of reversible nature and mainly disappeared by the end of the observation.
    [Abstract] [Full Text] [Related] [New Search]