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  • Title: Procainamide-induced agranulocytosis and thrombocytopenia.
    Author: Rothman IK, Amorosi EL.
    Journal: Arch Intern Med; 1979 Feb; 139(2):246-7. PubMed ID: 434983.
    Abstract:
    Procainamide therapy has frequently been reported as a cause of agranulocytosis, but severe thrombocytopenia associated with the use of this drug has been noted only once. We report a case of simultaneously occurring agranulocytosis and profound thrombocytopenia in a patient receiving procainamide hydrochloride. Different mechanisms appeared to be responsible for the two cytopenias.
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