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  • Title: Radioreceptor assay for prolactin and other lactogenic hormones.
    Author: Shiu RP, Kelly PA, Friesen HG.
    Journal: Science; 1973 Jun 01; 180(4089):968-71. PubMed ID: 4350405.
    Abstract:
    A radioreceptor assay with a sensitivity of 5 nanograms per milliliter has been developed for mammalian and avian pituitary prolactin, placental lactogenic hormones, and humnan growth hormone, using a membrane receptor preparation isolated from rabbit mammary glands. Prolactin preparations inhibited the binding of [(125)I]prolactin to receptors in direct proportion to the biological potency of these preparations. Thus, the radioreceptor assay provides a convenient and simnple assay for hormones which have lactogenic activity.
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