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  • Title: Discrimination between messenger ribonucleic acids by a mammalian translation initiation factor.
    Author: Nudel U, Lebleu B, Revel M.
    Journal: Proc Natl Acad Sci U S A; 1973 Jul; 70(7):2139-44. PubMed ID: 4352974.
    Abstract:
    A factor from rabbit-reticulocyte ribosome, which stimulates by 5-fold initiation of hemoglobin mRNA translation in Krebs ascites cell extracts, was purified to homogeneity. The factor, a protein of about 65,000 molecular weight in sodium dodecyl sulfate, discriminates between various mRNAs: it stimulates translation of alpha globin mRNA and of tobacco mosaic virus RNA, but has only a small effect on beta globin mRNA and no effect at all on Mengo virus RNA translation.
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