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Title: Contact sensitivity in vitro. The production of macrophage inhibition factors from DNCB sensitized lymphocytes by subcellular organelles obtained from DNCB epidermal tissue. Author: Nishioka K, Amos HE. Journal: Immunology; 1973 Sep; 25(3):423-32. PubMed ID: 4355043. Abstract: Actively allergized cells from guinea-pigs with contact sensitivity to DNCB were specifically triggered to produce the macrophage inhibition factors—antigen-dependent and non-antigen-dependent MIF by microsomal—DNCB complexes. The implication of this observation is that epidermal microsomal—DNCB complexes behave as complete antigens in a MIF assay system. It is therefore possible that such a combination acts as an immunogen in the induction of contact sensitivity to DNCB.[Abstract] [Full Text] [Related] [New Search]