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  • Title: Hepatitis A: detection by immune electron microscopy of a viruslike antigen associated with acute illness.
    Author: Feinstone SM, Kapikian AZ, Purceli RH.
    Journal: Science; 1973 Dec 07; 182(4116):1026-8. PubMed ID: 4356028.
    Abstract:
    Spherical 27-nanometer particles were visualized in stools obtained from hepatitis A patients in the acute phase of the disease. The particle was serologically specific for this disease, and every hepatitis A patient tested demonstrated a serologic response to this antigen. The findings suggest that it is the etiologic agent of hepatitis A.
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