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Title: Carcinogenic effect of N-bis(2-hydroxypropyl)nitrosamine by a single administration in rats. Author: Konishi Y, Ikeda T, Yoshimura H, Kawabata A, Mikami R. Journal: Cancer Lett; 1979 Feb; 6(2):115-9. PubMed ID: 436111. Abstract: The carcinogenic effect of a single intraperitoneal injection of N-bis)2-hydroxypropyl)nitrosamine (BHP) was studied in male Wistar rats. Lung tumors (adenomas and adenocarcinomas) had the highest incidence (100%). Fewer neoplasms were induced in the thyroid (adenomas and adenocarcinomas, 36%), kidney (renal cell carcinomas, 8%), and the sigmoid colon (adenomas and adenocarcinomas, 9%). No pancreatic neoplasms were found.[Abstract] [Full Text] [Related] [New Search]