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  • Title: Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression.
    Author: Wayne PK, Rosen OM.
    Journal: Proc Natl Acad Sci U S A; 1974 Apr; 71(4):1436-40. PubMed ID: 4364540.
    Abstract:
    Cyclic AMP concentrations were low for an adenylate cyclase-deficient mutant (cya(-)) and abnormally high for a catabolite receptor protein-deficient mutant (crp(-)). A fall in cellular cAMP concentration was always found when cells were subjected to transient repression. No consistent correlations were observed between catabolite repression and cellular cAMP levels.
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