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  • Title: [The clinical significance of hormone receptors in the treatment of breast cancer].
    Author: Trams G.
    Journal: Fortschr Med; 1979 Apr 12; 97(14):641-4. PubMed ID: 437632.
    Abstract:
    The assay of steroid receptors in tumor tissue has been shown to be a useful tool to evaluate the response of disseminated breast cancer to endocrine therapy. Principle and problems of this assay are outlined. An objective response of estrogen-receptor positive tumors to endocrine treatment can be achieved in about 60%. The rate of remissions in the receptor-negative group is below 10%. Possible explanations for false-positive or false-negative receptor assays are discussed. Additionally some possibilities for increasing the accuracy of the method are detailed.
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