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  • Title: Receptor binding studies on A1-(2-nitro-4-trimethylammoniophenyl)insulin.
    Author: Lesniak M, Gliemann J, Roth J, Easter BR, Sutton DA, Drewes SE.
    Journal: Hoppe Seylers Z Physiol Chem; 1979 Mar; 360(3):467-71. PubMed ID: 437696.
    Abstract:
    The results are presented from receptor binding studies and isolated fat cell assays on A1-(2-nitro-4-trimethylammoniophenyl)insulin. In the former tests, the derivative is shown to have properties similar to native insulin and the fat cell assays afford a value of 76 +/- 4%. The importance of a charged, hydrophilic moiety attached at A1-glycine is discussed in the light of the above findings.
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