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  • Title: Inhibition by antihistamines of the vascular permeability increase induced by bradykinin.
    Author: Becker EL, Mota I, Wong D.
    Journal: Br J Pharmacol; 1968 Oct; 34(2):330-6. PubMed ID: 4386856.
    Abstract:
    1. Mepyramine and triprolidine hydrochloride have a marked inhibitory effect on the local increase of vascular permeability induced by bradykinin.2. The anti-bradykinin effect of both antihistamines was species dependent, being evident in rabbits, rats and mice but not in guinea-pigs.
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