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  • Title: Treatment of stage D hormone-resistant carcinoma of the prostate with estramustine phosphate.
    Author: Benson RC, Wear JB, Gill GM.
    Journal: J Urol; 1979 Apr; 121(4):452-4. PubMed ID: 439216.
    Abstract:
    We report on 51 patients with hormone-resistant, stage D prostatic carcinoma who were treated with estramustine phosphate and followed for at least 6 months. Of the 51 patients 5 (10 per cent) had a partial objective response, 30 (59 per cent) remained stable and 16 (31 per cent) had progression of the disease. All of those patients who had a partial response or remained stable also experienced subjective improvement as judged by relief of pain and performance status. Approximately 8 per cent of the patients will be unable to take estramustine phosphate because of intolerable gastrointestinal side effects.
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