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  • Title: Severe mannitol-induced hyponatremia complicating transurethral prostatic resection.
    Author: Kirschenbaum MA.
    Journal: J Urol; 1979 May; 121(5):687-8. PubMed ID: 439271.
    Abstract:
    A case is presented in which the absorption of mannitol irrigation solution across prostatic veins resulted in severe hyponatremia in a patient undergoing transurethral prostatic resection. Since hyposmolality of the extracellular fluid was not seen because of the presence of mannitol the patient was asymptomatic despite a rapid decrease in the serum sodium concentration to 99 mEq./l. The importance of distinguishing dilutional hyponatremia from hyponatremia with normal or elevated osmolality is discussed.
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