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  • Title: Physiologic and pharmacologic studies of the human oviduct.
    Author: Coutinho EM.
    Journal: Fertil Steril; 1971 Dec; 22(12):807-15. PubMed ID: 4399584.
    Abstract:
    Tubal motility during the menstrual cycle was measured in women by means of an indwelling polyvinyl catheter. During all phases of the cycle, there were episodes of tubal motility at regular intervals. These episodes were more frequent during menstruation but the intensity and duration were greater during the proliferative phase. During the luteal phase the intensity and duration of the outburst were depressed. The episodes of motor activity were asynchronous between the 2 tubes and between different portions of the same tube. Activity in the rabbit was similar to that of the human and was found in the isthmic and ampullar portions of the tube but not in the infundibulum. Intravenous administration of epinephrine or norepinephrine increased motility. Alpha-adrenergic blockade with phentolamine mesylate and phenoxybenzamine suppressed spontaneous outbursts in the rabbit. The tubes were sensitive to oxytocin but almost insensitive to vasopressin. Suction of the breast increased tubal motility.
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