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  • Title: Abolition of the nerve-induced responses of the isolated vas deferens of the young rat by agents blocking -adrenoceptors.
    Author: Swedin G.
    Journal: Br J Pharmacol; 1972 Jan; 44(1):160-1. PubMed ID: 4401307.
    Abstract:
    The mechanical responses of isolated fieldstimulated vasa deferentia from rats 3-10 days old were abolished by low doses of drugs blocking alpha-adrenoceptors. In preparations from older animals this effect was absent or there was a potentiation of the responses. The effect of atropine also changed during postnatal development. In the early period a moderate (10-40%) decline of the nerve-induced responses was generally observed, but later even high concentrations of atropine were without effect.
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