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  • Title: Effects of gamma-hydroxybutyrate on chick behaviour, electrocortical activity and crossed extensor reflexes.
    Author: Osuide G.
    Journal: Br J Pharmacol; 1972 Apr; 44(4):593-604. PubMed ID: 4402818.
    Abstract:
    1. Convulsant and anticonvulsant effects of gamma-hydroxybutyrate (GHB) have been studied in chicks.2. When administered alone, GHB produced weak myoclonic seizures accompanied by electrocortical synchrony and spikes.3. GHB was found to protect chicks against leptazol- and picrotoxin-induced seizures. A slight potentiation of strychnine-induced seizures was evident.
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