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  • Title: Relation of HVH-II to carcinoma of the cervix.
    Author: Tobin SM, Fish EN, Cooter NB, Papsin FR.
    Journal: Obstet Gynecol; 1979 May; 53(5):553-8. PubMed ID: 440666.
    Abstract:
    An animal model is described that demonstrates the development of varying degrees of basal cell hyperplasia, metaplasia, and dysplasia following cervicovaginal herpesvirus hominis type II (HVH-II) infection. Although the study spanned a period of 30 months, the equivalent of 60 human years, there was no evidence of anaplasia. These results are considered in relation to the role of HVH-II as an initiator in the multistep process leading to cervical carcinoma.
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