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  • Title: Dysplasia and the pill--a progress report on the American Women's Health Program.
    Author: Hontz AC, Balin H, Merritt CG, LoSciuto A.
    Journal: J Reprod Med; 1974 Sep; 13(3):101-5. PubMed ID: 4412876.
    Abstract:
    25,000 contracepting women attending family planning facilities in 1 3 clinical units in the United States and Puerto Rico have been enrolled in a study to determine the relationship, if any, of method of contraception to cervical dysplasia. Although the investigators are not yet in a position to report on any association or nonassociation, certain aspects of the study are described. Personal characteristics of those patients with dysplasia or cancer of the cervix detected at the time of enrollment will be compared, retrospectively, in the months ahead with the characteristics of the remainder of the cohort. The scope of work involved in defining the "prevalence" cases encompases retesting patients whose enrollment smears were diagnosed cytologically as unsatisfactory, neoplasm uncertain, or mild to moderate dysplasia. T he screening technique of 2 sequential cervical scrapings results in an increase of 50% of cytologically detected cases as compared with a single scrape. Approximately 80% of pill acceptors are 29 years old or less compared with 70% of the IUD users and 50% of the users of other methods. The pill acceptors comprise 51% of the total group, the IUD users, 31%, and users of other methods, 19%. It appears that in this analysis choice of contraception as a possible variable of cervical neoplasia rates will not be confounded with age at first coitus.
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