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  • Title: [The effect of unconjugated bile salts on the intestinal absorption of electrolytes and water in the proximal jejunum. Studies in conscious rats (author's transl)].
    Author: Konder H, Dennhardt R, Haberich FJ.
    Journal: Res Exp Med (Berl); 1979 Apr 23; 175(1):37-49. PubMed ID: 441524.
    Abstract:
    With an in vivo-perfusion-technique the influence of unconjugated bile salts (cholate, desoxycholate) on the net electrolyte and volume absorption is studied in the jejunum of conscious rats. The applied doses correspond to physiological concentrations in the intestine of rats. Control experiments were performed in the same animal. Cholate and desoxycholate diminish the net electrolyte and volume absorption resp. cause a net secretion. The effects are largely reversible. The extent of net volume absorption depends on the applied dose of each bile salt. The possible mode of action of unconjugated bile salts on the electrolyte and water absorption in the small intestine is discussed.
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