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  • Title: Treatment of methapyrilene toxicity with physostigmine.
    Author: Temple AR, English PH.
    Journal: Vet Hum Toxicol; 1979 Apr; 21(2):84-6. PubMed ID: 442480.
    Abstract:
    Methypyrilene, 40 mg/kg, was administered to male mongrel dogs, resulting in both central and peripheral anticholinergic effects. Physostigmine in doses of 0.5 to 1.0 mg was effective in reversing the central effects completely and the peripheral effects to a limited degree.
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