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  • Title: Variability in erythrocyte deformability among various mammals.
    Author: Smith JE, Mohandas N, Shohet SB.
    Journal: Am J Physiol; 1979 May; 236(5):H725-30. PubMed ID: 443394.
    Abstract:
    Deformability is an important aspect of erythrocyte physiology and has been extensively studied using human red cells. We have studied erythrocytes from 25 different animals using a viscometric technique. Erythrocyte diameters ranged from 3.3 microns in the goat to 11.4 microns for the elephant seal. Erythrocytes from most species deformed readily when a fluid shear stress was applied. A deformability index of the stressed cell defined as (length - width)/(length + width) correlated with cell size. The erythrocytes of four animals (pygmy goat, goat, Batanga horse, and miniature horse) deformed less than most species. Camel and llama erythrocytes, which were ellipsoidal, did not deform but oriented in the stress field.
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