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  • Title: [Monitoring of the induction of labour by prostaglandin f2alpha in early pregnancy (author's transl)].
    Author: Wiechell H, Massenbach W.
    Journal: Geburtshilfe Frauenheilkd; 1974 Sep; 34(9):767-75. PubMed ID: 4437567.
    Abstract:
    Compared to conventional methods, therapeutic abortion up to the 12th week of gestation by the extraamnial administration of (PG) prostaglandin is undesirable because of the long-term treatment necessary and because of the danger of ascending infection. However, in cases of late therapeutic abortion, missed abortion, and hydatidiform mole, the administration of PG is the method of choice. Continuous monitoring of the intrauterine pressure during intermittent administration of PG in dosages which do not unduly prolong the time of therapy shows pathological patterns of contractions due to overstimulation of the uterus. Initial uterine tetany then shows discoordination of the contractions, high frequency of the contractions, and during the 2nd stage, excessively high intrauterine pressures. It is therefore necessary to individualize the dosage of PG according to the uterine response measured by continuous monitoring of the intrauterine pressures. (author's modified)
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