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  • Title: Comparison of abortion performed with prostaglandin F2 alpha and hysterotomy.
    Author: Koeffler H, Tervilä L.
    Journal: Ann Chir Gynaecol Fenn; 1974; 63(6):483-6. PubMed ID: 4441029.
    Abstract:
    A comparative study of prostaglandins F2 alpha induced abortion and hysterotomy is presented. The intraamniotic and extraamniotic procedures were employed, using doses of 40 mg and 2.5-5.0 mg of prostaglandin, respectively. Failure to abort by the intraamniotic method occurred in 8% of the cases (50 patients), whereas the failure rate with the extraamniotic method was 42% (51 patients). Oxytocin infusion was administered to 14 of the 30 successful cases in the extraamniotic group and to 16 of the 46 successful cases in the intraamniotic group. No severe side effects occurred except for 1 case of cervical rupture in the intraamniotic group. Nausea and vomiting were the most common side effects. Blood pressure fell significantly in 12 patients in the intraamniotic group, although the decrease was transitory. 14 patients in the intraamniotic group required analgesics for pain. The average hospital stay for intraamniotic patients was 4 days less than for hysterotomy patients.
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