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  • Title: [In vitro effects of saluretics, osmotic pressure and the acidity of the medium on the evaluated globular volume in chronic bronchopneumopathies by means of microhematocrit].
    Author: Fumagalli G, Ferrara A, Bonsignore G.
    Journal: Minerva Med; 1974 Dec 22; 65(92):4876-83. PubMed ID: 4449619.
    Abstract:
    The in vitro effect of diuretics, osmotic pressure and acidity of the medium on red cell volume was examined. The results showed that:1) diuretics lead to a reduction in volume;2) this reduction is enhanced at higher concentrations; 3) the effect is more noticeable in more diluted blood; 4) a decrease in volume is also displayed by cells whose volume has been increased by hypo-osmotic solutions; 5) this effect is not apparent when cell volume is reduced to the minium by hypersmotic solutions;6) the effect of the pH value is only felt in the case of extreme variations.
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