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  • Title: Phase II study of 5-fluorouracil, methyl-CCNU, and daunorubicin in colorectal cancer: a Cancer and Leukemia Group B study.
    Author: White LA, Perry MC, Kardinal CG, Kennedy BJ, Weiss RB, Carey RW.
    Journal: Cancer Treat Rep; 1979 Feb; 63(2):215-7. PubMed ID: 445497.
    Abstract:
    The three-drug combination of 5-fluorouracil, methyl-CCNU, and daunorubicin was evaluated in 38 patients with unresectable or metastatic carcinoma of the colon. There were five partial responses and one complete response for an overall response rate of 16%. Although toxicity was tolerable, daunorubicin failed to add to the 5-fluorouracil and methyl-CCNU combination.
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