These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: NN'-diacetylchitobiase activity in Tay-Sachs disease and Sandhoff's disease.
    Author: Stirling JL.
    Journal: Biochem J; 1974 Aug; 141(2):597-9. PubMed ID: 4455225.
    Abstract:
    In Tay-Sachs disease and Sandhoff's disease respectively, one of the N-acetyl-beta-hexosaminidases (form A) or both (forms A and B) are absent, but glycosaminoglycans containing N-acetylhexosamines are not accumulated. The presence of NN'-diacetylchitobiase in livers from patients with these diseases raises the possibility that this new enzyme is involved in the metabolism of glycosaminoglycans rather than the enzymes previously described.
    [Abstract] [Full Text] [Related] [New Search]