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  • Title: Gallbladder bile peptides and their structure.
    Author: Konomi K, Yamamoto H, Nishimura M.
    Journal: Jpn J Surg; 1974 Mar; 4(1):48-55. PubMed ID: 4459485.
    Abstract:
    Human gallbladder bile was separated by salting-in column chromatography using silica gel ammonium sulfate system. The second fraction containing peptides was found to vary in cholelithiasis in relation to Fraction 1. To determine the structure of the peptides, bovine gallbladder bile was fractionated by salting out method with ammonium sulfate. Four peptides were isolated and their amino acid sequences were determined to be: (see article).
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