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  • Title: The role of M protein in phagocytosis. II. Opsonization of Streptococcus pyogenes in vitro.
    Author: Tylewska S, Hryniewicz W.
    Journal: Zentralbl Bakteriol Orig A; 1979 Oct; 245(1-2):44-7. PubMed ID: 44622.
    Abstract:
    Opsonization of two different streptococcal group A type 12 strains was investigated. The strains differed only in M protein presence. It was observed that after the treatment of bacteria with fresh normal rabbit serum M positive strains bind to their surface IgG only whereas M negative strains solely some complement components. These results may suggest that streptococci lacking M protein are able to activate complement by alternate pathway.
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