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  • Title: [Chronobiological approach to monthly rhythms of healthy women, with spontaneous menses (author's transl)].
    Author: Reinberg A, Smolensky MH, Ghata J, Gervais A, Gervais P.
    Journal: Ann Endocrinol (Paris); 1974; 35(3):309-10. PubMed ID: 4463804.
    Abstract:
    A set of physiological variables were studied in 5 healthy women having spontaneous menses to determine menstrual cycle modifications of circadian rhythms. Data were gathered at 4-hour intervals over 24 hours on Days 1, 8, 15, 22, and 29 of menses. The acrophases of the menstrual rhythms for the various parameters were as follows: rectal temperature, Day 23; skin reactivity to histamine, Day 30; urinary water, Day 21; estrogens, Day 19; pregnanediol, Day 20; 17-hydroxycorticosterone (17-OH CS), Day 19. Menstrual variations in the timing of the circadian acrophase were also found for urinary 17-OHCS, 17-ketosterone, and potassium as well as for pain threshold and skin reaction to histamine. These results suggest that the adrenal gland and ovary are phased by the menstrual cycle.
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