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  • Title: Fatty-acid synthesis in lactating-goat mammary gland. 1. Medium-chain fatty-acid synthesis.
    Author: Grunnet I, Knudsen J.
    Journal: Eur J Biochem; 1979 Apr; 95(3):497-502. PubMed ID: 446475.
    Abstract:
    Tissue slices from lactating goat-mammary gland synthesized short (C4:0 and C6:0), medium (C8:0 and C10:0) and long-chain (C12:0 to C16:0) fatty acids in proportions similar to that found in goat milk fat. In contrast, the particle-free supernatant fraction and the purified fatty acid synthetase from this tissue synthesized predominantly short-chain and long-chain fatty acids. Terminating acyl-thioesterases of low molecular weight could not be detected in the particle-free supernatant. Addition of the microsomal fraction to the particle-free supernatant induced the synthesis of medium-chain fatty acids in proportions which were similar to those found in goat milk fat.
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