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  • Title: Serological comparison of five arginine-utilizing Mycoplasma species by two-dimensional immunoelectrophoresis.
    Author: Thirkill CE, Kenny GE.
    Journal: Infect Immun; 1974 Sep; 10(3):624-32. PubMed ID: 4473427.
    Abstract:
    Five arginine-utilizing, nonglycolytic Mycoplasma species were compared serologically by two dimensional immunoelectrophoresis. The survey included: Mycoplasma hominis, Mycoplasma arthritidis, Mycoplasma gateae, Mycoplasma gallinarum, and three strains of Mycoplasma arginini. Although the M. arginini strains showed strong cross-reactions, each strain produced a different antigenic profile which was distinct and which indicated significant antigenic differences between strains. The M. arginini strains showed strong relationships with M. gateae; lesser cross-reactions were observed with other strains. Common antigens were demonstrable in the entire group. When all these species were compared with a glycolytic species, Mycoplasma gallisepticum, no cross-reactions were observed. Two-dimensional immunoelectrophoresis was a far more sensitive technique than double-immunodiffusion since as many as 20 components could be resolved.
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