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  • Title: Treatment of acute bacterial bronchitis and pneumonia with cefaclor.
    Author: Mogabgab WJ, Pollock B, Beville RB, Gentry LO, Jemsek JG.
    Journal: Postgrad Med J; 1979; 55 Suppl 4():62-6. PubMed ID: 44908.
    Abstract:
    Sixty patients with pneumonia and/or bronchitis were treated with cefaclor, a new orally administered cephalosporin. Of those 60, 27 adults were treated with 500 mg every 8 hours, 26 adults with 250 mg every 6 hours, and 7 children with 50 mg/kg/day. In the adults, pneumonia was caused most frequently by Streptococcus pneumoniae and Haemophilus influenzae. The 7 children had pneumococcal pneumonia. All but 2 adults, both elderly patients with chronic obstructive pulmonary disease, were successfully treated. One instance of drug hypersensitivity occurred. All 7 children responded rapidly, with no side effects, to cefaclor therapy.
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