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  • Title: Genetic modification of electric properties in an excitable membrane (paramecium-calcium conductance-electrophysiological measurements-membrane mutant).
    Author: Kung C, Eckert R.
    Journal: Proc Natl Acad Sci U S A; 1972 Jan; 69(1):93-7. PubMed ID: 4500559.
    Abstract:
    A behavioral deficiency produced by a single gene mutation in Paramecium aurelia was traced to impaired electric excitability of the cell membrane. Evidence is presented that the mutant membrane does not exhibit the normal depolarization-activated increase in calcium conductance responsible for regenerative depolarization in the wild type. Other electric properties characteristic of the wild-type membrane remain normal in the mutant.
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