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  • Title: Transamidase reactions involved in the enzymic coagulation of semen: isolation of -glutamyl- -lysine dipeptide from clotted secretion protein of guinea pig seminal vesicle.
    Author: Williams-Ashman HG, Notides AC, Pabalan SS, Lorand L.
    Journal: Proc Natl Acad Sci U S A; 1972 Aug; 69(8):2322-5. PubMed ID: 4506101.
    Abstract:
    New supportive evidence is advanced in favor of the hypothesis that the enzymic coagulation of guinea pig semen involves transamidase reactions that result in the formation of gamma-glutamyl-epsilon-lysine intermolecular cross linkages between molecules of a basic protein in seminal vesicle secretion. The dipeptide gamma-glutamyl-epsilon-lysine was isolated in large quantities from proteolytic digests of the coagulated basic vesicular secretion protein that comprises the seminal clot.
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