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  • Title: Cyclic chemotherapy in acute lymphoblastic leukaemia of childhood: 5-year survivals.
    Author: Vowels MR, Willoughby ML.
    Journal: Arch Dis Child; 1973 Jun; 48(6):436-40. PubMed ID: 4514541.
    Abstract:
    Of 31 children with acute lymphoblastic leukaemia treated with a cyclical scheme of chemotherapy, 19% survived for over 5 years, 16% remained in continuing haematological remission for 5 years, and 13% remained leukaemia free for 5 years. These findings are relevant to potential cure, unlike the median remission duration, which is a measure of palliation. A relation between the percentage of PAS-positive blast cells at diagnosis and duration of control of the disease still pertains for the long-term results in this series of patients.
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