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  • Title: Free ribosomal RNA genes in the macronucleus of Tetrahymena.
    Author: Gall JG.
    Journal: Proc Natl Acad Sci U S A; 1974 Aug; 71(8):3078-81. PubMed ID: 4528573.
    Abstract:
    In the macronucleus of the ciliated protozoan, Tetrahymena pyriformis GL, the genes coding for 17S and 25S rRNA exist as free, extrachromosomal molecules. About 90% of the molecules are linear with a molecular weight of 12.6 x 10(6). Most of the remainder are circles of the same size, or lariats (circles with tails). A few dimers and oligomers are found. The extrachromosomal rDNA of Tetrahymena represents a kind of gene amplification that may be common among primitive eukaryotes.
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