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  • Title: Voltage clamp experiments of single muscle fibers of Rana pipiens.
    Author: Moore LE.
    Journal: J Gen Physiol; 1972 Jul; 60(1):1-19. PubMed ID: 4537778.
    Abstract:
    A voltage clamp for single muscle fibers has been developed. Stability of the system was achieved when an artificial node was created by enclosing a single muscle fiber in a petroleum jelly seal which served as an analogue of the myelin sheath. Typical voltage clamp records were obtained with large inward transient currents followed by a delayed rectification of the outward currents. These currents looked qualitatively similar when the transverse tubular system was destroyed. Errors in current measurement, especially those due to anomalous rectification, are discussed.
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