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  • Title: Rosette formation by mouse lymphocytes. III. Receptors for immunoglobulin on normal and activated T cells.
    Author: Soteriades-Vlachos C, Gyöngyössy MI, Playfair JH.
    Journal: Clin Exp Immunol; 1974 Oct; 18(2):187-92. PubMed ID: 4549625.
    Abstract:
    By the use of an indirect immunofluorescent method for the identification of mouse T lymphocytes forming rosettes with antibody-coated erythrocytes, it was found that about 10% of the T cells in normal mouse spleen have receptors for antibody. Inhibition experiments with purified aggregated immunoglobulins showed that IgG2 is the major class involved. The same receptor was found on T cells activated against H-2 isoantigens. The importance of using the appropriate red cells and antiserum for demonstrating receptors on T cells is stressed.
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