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Title: Cytochalasin B: does it affect actin-like filaments? Author: Forer A, Emmersen J, Behnke O. Journal: Science; 1972 Feb 18; 175(4023):774-6. PubMed ID: 4550685. Abstract: An in vitro system was used to test the purported action of cytochalasin B. At concentrations 100 times those used for experiments in vivo, cytochalasin B did not cause the breakdown of F-actin, did not inhibit the transformation of G-actin to F-actin, did not inhibit the binding of heavy meromyosin to F-actin, and did not inhibit the adenosine triphosphate-induced release of heavy meromyosin from F-actin.[Abstract] [Full Text] [Related] [New Search]