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  • Title: Effect of cimetidine on chronic gastric ulcers produced experimentally in rats.
    Author: MacPherson BR, Kilam SK.
    Journal: Can J Surg; 1979 Jul; 22(4):385-7. PubMed ID: 455171.
    Abstract:
    The authors have studied the effects of cimetidine on the healing of chronic gastric ulcers induced in rats. Gastric ulcers were produced by topical application of 60% acetic acid to the serosal surface of the lesser curvature of the stomach. Oral administration of cimetidine, 150 mg/kg daily, in two divided doses for a maximum of 14 days failed to produce any significant acceleration of healing.
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