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  • Title: Relation between protein synthesis and phospholipid synthesis and turnover in Escherichia coli.
    Author: Crowfoot PD, Esfahani M, Wakil SJ.
    Journal: J Bacteriol; 1972 Dec; 112(3):1408-15. PubMed ID: 4565543.
    Abstract:
    Turnover of phospholipids occurred continuously in a fatty acid auxotroph of Escherichia coli, but in the wild-type parent strain significant turnover occurred only under conditions where protein synthesis was inhibited but lipid synthesis continued. Both strains gave a stringent response of ribonucleic acid accumulation to amino acid starvation, but only in the wild type was lipid synthesis also inhibited. A revertant strain of the auxotroph resembled the wild type in this respect. The phospholipid that accumulates in the culture medium as a result of the lipid turnover appears to be part of a loosely bound low-density complex arising from the cell envelope.
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