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Title: The synthesis of epsilon-rhodomycinone- and carminomycin-11-methyl ethers. Author: Essery JM, Doyle TW. Journal: J Antibiot (Tokyo); 1979 Mar; 32(3):247-9. PubMed ID: 457585. Abstract: The conversion of epsilon-rhodomycinone to its 11-methyl ether via selective hydrolysis of the 4,6,7,11-tetraacetate is described. This series of reactions was used as a model for the conversion of carminomycin to its 11-methyl ether. The anti-tumor activity of the latter compound was less than that of both carminomycin and its 4-methyl ether (daunomycin).[Abstract] [Full Text] [Related] [New Search]