These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Methyltetrahydrofolic acid mediates N- and O-methylation of biogenic amines.
    Author: Banerjee SP, Snyder SH.
    Journal: Science; 1973 Oct 05; 182(4107):74-5. PubMed ID: 4581052.
    Abstract:
    A variety of mammalian and avian tissues N- and O-methylate indoleamines and phenylethylamines, with methyltetrahydrofolic acid as the methyl donor. Because it is considerably more efficient than S-adenosylmethionine, methyltetrahydrofolic acid may be the natural methyl donor in this reaction. With methyltetrahydrofolic acid, serotonin is O-methylated to 5-methoxytryptamine, a novel indoleamine in mammalian brain.
    [Abstract] [Full Text] [Related] [New Search]