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  • Title: A mutant of Escherichia coli with a new, highly efficient promoter for the lactose operon.
    Author: Bruenn J, Hollingsworth H.
    Journal: Proc Natl Acad Sci U S A; 1973 Dec; 70(12):3693-7. PubMed ID: 4590169.
    Abstract:
    We have isolated a mutant of E. coli whose maximal rate of synthesis of lac mRNA is 25-fold greater than that of its parental wild-type strain. The mutant also shows alterations in the kinetics of beta-galactosidase synthesis, the functional half-life of beta-galactosidase mRNA, and the properties of lac repressor.
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