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  • Title: [Intensity of DNA synthesis in animal organs after a flight on the Kosmos-782 biosatellite].
    Author: Guseĭnov FT, Egorov IA, Komolova GS, Tigranian RA.
    Journal: Kosm Biol Aviakosm Med; 1979; 13(4):30-3. PubMed ID: 459398.
    Abstract:
    With respect to H3-thymidine incorporation the rate of DNA synthesis in the liver, spleen and thymus of rats was determined in flight and synchronous rats. Six hours post-flight the rate of H3-thymidine incorporation into the liver of flight rats did not differ from the normal (vivarium controls) and was 50% higher than in the synchronous rats. In the spleen and thymus of flight animals this parameter was 60 and 33% below the norm. Similar but less pronounced changes in the spleen were found in the synchronous rats. Twenty-five days postflight the rate of DNA synthesis in lymph organs recovered completely and tended to increase, whereas in the liver it remained significantly below the norm.
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