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Title: Genetic recombination in bacteriophage phi chi 174. Author: Benbow RM, Zuccarelli AJ, Davis GC, Sinsheimer RL. Journal: J Virol; 1974 Apr; 13(4):898-907. PubMed ID: 4595301. Abstract: Genetic recombination in bacteriophage phiX174 usually takes place early in the infection process and involves two parental replicative form (double-stranded) DNA molecules. The host recA protein is required; none of the nine known phiX174 cistron products is essential. The products of a single recombination event are nonreciprocal and asymmetric. Typically, only one of the parental genotypes and one recombinant genotype are recovered from a single cell. An alternative, less efficient recombination mechanism which requires an active phiX174 cistron A protein is observed in the absence of the host recA gene product.[Abstract] [Full Text] [Related] [New Search]