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Title: In vitro repair of apurinic sites in DNA. Author: Verly WG, Gossard F, Crine P. Journal: Proc Natl Acad Sci U S A; 1974 Jun; 71(6):2273-5. PubMed ID: 4601584. Abstract: Apurinic sites disappear from DNA during an incubation of the DNA with the Escherichia coli endonuclease specific for apurinic sites, DNA polymerase I (EC 2.7.7.7.), and T4 ligase (EC 6.5.1.1). Omission of any one of these three enzymes and, in particular, omission of the endonuclease specific for apurinic sites prevents this in vitro repair.[Abstract] [Full Text] [Related] [New Search]