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  • Title: Cyclophosphamide treatment in steroid-sensitive nephrotic syndrome of childhood.
    Author: Barratt TM, Bercowsky A, Osofsky SG, Soothill JF.
    Journal: Lancet; 1975 Jan 11; 1(7898):55-8. PubMed ID: 46019.
    Abstract:
    An 8-week course of 3 mg. per kg. body-weight per day of cyclophosphamide was administered to eighty-two children with steroid-senstitive nephrotic syndrome. One died, and of the remainder, 69% were in remission after 1 year and 44% after 4-years. Older children and those in whom cyclophosphamide was given during a steroid-maintained remission fared better.
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