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  • Title: [Theoretical analysis of action of substrate analogs in dissociating enzyme systems].
    Author: Kurganov BI.
    Journal: Mol Biol (Mosk); 1979; 13(3):649-55. PubMed ID: 460211.
    Abstract:
    The action of substrate analogue inable to catalytic conversion has been analysed in dissociating enzyme system of the type 2p in equilibrium with P (P is enzyme oligomer and p is its half). The regions of parameters corresponding to dependences of enzyme reaction rate (v) on substrate analogue (H) concentration with maximum are calculated. It is characteristic of dissociating enzyme systems that the appearance of maximum depends on enzyme concentration. It has also been demonstrated that at definite values of parameters and values of enzyme and substrate concentration the v versus [H]o plots may show an intermediate plateau, maximum and its preceding S-shape or maximum and minimum simultaneously.
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