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Title: Maternal nutrition and fetal growth. Journal: Nutr Rev; 1974 Aug; 32(8):241-3. PubMed ID: 4602698. Abstract: R.L. Naeye et al, Effects of Maternal Nutrition on the Human Fetus, Pediatrics, 52: 494-503, 1973, have further extended their study of the effects of maternal nutrition on fetal growth. 467 cases between 18 and 44 weeks gestational stage were chosen out of 1044 consecutive necropsies carried out on still-and new-born infants in one hospital between 1960 and 1968. 4 subgroups were defined on the basis of the mother's nutritional status before and during pregnancy, as well as height and weight. Mothers were classified as being over- or under-weight by comparison of their weight at the time of booking with published standards. They were further classified into high and low weight gain groups and according to whether they received general dietary advice or more specific recommendations to limit weight gain during pregnancy. At each necropsy, morphometric techniques were used to estimate the number of cells and the cytoplasmic and nuclear mass of cells in the liver and adrenals, two organs which previous studies had shown to be particularly affected by fetal undernutrition. The mean value for all measurements fell progressively as the nutritional status of the mother worsened, the order of the groups being: 1) overweight, high weight gain; 2) underweight, high weight gain; 3) overweight, low weight gain; and 4) underweight, low weight gain. The effect is particularly manifest after 33 weeks of gestation. The reviewer concludes that the undesirable consequence of strict dietary restrictions during pregnancy must now be abundantly clear and should receive wide publicity.[Abstract] [Full Text] [Related] [New Search]